issue是問(wèn)題，議題。environmental issues，環(huán)境問(wèn)題。economic issue，經(jīng)濟(jì)問(wèn)題。通常比較正式，與政治方面有些關(guān)系，很官方。 problem指需要解決的問(wèn)題、難題等，常與動(dòng)詞solve搭配。

problem: 指客觀上存在的、難以處理或難以理解的問(wèn)題。issue: 多指意見(jiàn)能達(dá)到一致的問(wèn)題，但要通過(guò)爭(zhēng)論或討論解決。

problem 泛指（數(shù)學(xué),物理等）難題或待解決的問(wèn)題,如：This problem on the environmental protection floored the new mayor.這個(gè)關(guān)于環(huán)境保護(hù)的問(wèn)題把新任市長(zhǎng)難住了.

issue 一般指社會(huì),政治,經(jīng)濟(jì)等方面的大問(wèn)題.The mayor is challenged with a big economic problem.那位市長(zhǎng)面臨著一個(gè)經(jīng)濟(jì)方面的問(wèn)題.

issue：n.問(wèn)題,議題; 爭(zhēng)論點(diǎn)。主要是用來(lái)形容一些爭(zhēng)論,一些不共同認(rèn)可的差異。
There was no issue at all between us.
我們之間毫無(wú)爭(zhēng)議.
problem：n.問(wèn)題,疑難問(wèn)題，是表示特別難的難題,還常常被用來(lái)表示作業(yè)難題等。
These problems are the result of years of bad management.
這些問(wèn)題是多年經(jīng)營(yíng)不善造成的后果.